R. da Silva Antunes

This study maps human CD4+ T cell responses to Bordetella pertussis across its genome, revealing broad reactivity and similar polarization regardless of vaccination history.

The paper examines immune responses in vaccinated individuals during SARS-CoV-2 breakthrough infection, showing early activation of memory T cells and subsequent neutralizing antibody production.

The paper assesses immunological memory to Common Cold Coronaviruses over three years and finds sustained CD4+ T cell and antibody responses, suggesting stable memory rather than frequent reinfections.

This study shows that SARS-CoV-2 vaccines induce T cell responses that cross-recognize variants from Alpha to Omicron, with high preservation of CD4+ and CD8+ T cell epitopes.

This study develops a T cell-based method to distinguish between SARS-CoV-2 infection and vaccination by analyzing T cell reactivity to specific epitopes, achieving high classification accuracy across different groups.

The paper analyzes T cell responses to SARS-CoV-2 variants and finds minimal impact on CD4+ and CD8+ T cell reactivity in convalescents and vaccinees.

The paper identifies SARS-CoV-2 epitopes recognized by CD4+ and CD8+ T cells in COVID-19 patients and develops epitope megapools for their detection.