circPCMTD1: A protein-coding circular RNA that regulates DNA damage response in BCR/ABL-positive leukemias
D. Papaioannou, A. P. Urs, R. Buisson, A. Petri, R. Kulkarni, D. Nicolet, L. Woodward, C. Goda, K. Mrozek, G. K. Behbehani, S. Kauppinen, A.-K. Eisfeld, I. Aifantis, G. Singh, A. M. Dorrance, R. Garzon
This study identifies circPCMTD1 as a circular RNA that promotes leukemic cell proliferation by enhancing DNA damage response tolerance through a novel peptide product.
bioRxiv · Jun 27, 2024Cancer Biology