Author

R. Hamelin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

F. Armand· 3 shared A. Dufour· 1 shared A. Ignacio· 1 shared A. Sirvent· 1 shared C. A. Thomson· 1 shared E. APONTE· 1 shared E. Fourgous· 1 shared F. Radtke· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

F. Armand

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Resistance mechanism to Notch inhibition and combination therapy in human T cell acute lymphoblastic leukemia

L. Cao, G. A. Ruiz Buendia, N. Fournier, Y. Liu, F. Armand, R. Hamelin, M. Pavlou, F. Radtke

The paper identifies PIK3R1 loss as a resistance mechanism to NOTCH inhibition in T-ALL and shows CDK4/6 inhibitors synergize with NOTCH inhibitors.

Blood Advances · Oct 24, 2023Peer-reviewedCancer Biology

Regulation of Src tumor activity by its N-terminal intrinsically disordered region

E. APONTE, M. Lafitte, A. Sirvent, V. Simon, M. barbery, E. Fourgous, M. Maffei, F. Armand, R. Hamelin, J. Pannequin, P. P. Fort, M. Pons, s. roche

This study identifies the ULBR in Src as essential for its oncogenic activity by modulating membrane substrate phosphorylation.

bioRxiv · May 10, 2021Cancer Biology

Small Intestinal Resident Eosinophils Maintain Gut Homeostasis Following Microbial Colonisation

K. Shah, A. Ignacio, J. Bernier-Latmani, Y. Koeller, G. Coakley, M. Moyat, R. Hamelin, F. Armand, N. C. Wong, H. Remay, C. A. Thomson, R. Bukhard, A. Dufour, T. V. Petrova, N. L. Harris, K. D. McCoy

This study identifies eosinophils as critical regulators of intestinal homeostasis, barrier integrity, and motility following microbial colonization.

bioRxiv · Jan 30, 2021 · PreprintImmunology