R. K. Jha

This study identifies key residues in SARS-CoV-2 RBD that enhance binding to ACE2 compared to SARS-CoV through long simulations and force field comparisons.

This paper designs a pH-sensitive Protein G-IgG interaction that shows a 50-fold change in binding affinity when pH shifts from acidic to basic.

This study tests the antiviral effect of Cynodon dactylon extract on IMNV in shrimp, finding 98% survival rate with extract treatment.

This paper tests a natural oil blend (NOBF) against ASFV in porcine alveolar macrophages, finding it deactivates the virus at high dilutions.

This paper shows that Mtb's SufR senses NO via its 4Fe-4S cluster, regulates Fe-S cluster biogenesis, and supports persistence in mice.

This study identifies a multifunctional DNA/RNA topoisomerase in mycobacteria that performs RNA hydrolysis and rRNA processing, highlighting its dual catalytic roles in RNA metabolism.

This paper shows that the effectiveness of the β-lactam/β-lactamase inhibitor combination against Mtb depends on WhiB4-regulated redox changes, with higher mycothiol redox potential enhancing drug efficacy.