R. Kuemmerli

The paper develops a co-evolution algorithm to predict bacterial iron interaction networks based on siderophore synthetase-receptor gene pairs across Pseudomonas genomes, revealing habitat- and pathogen-specific interactions.

The paper tracks gene expression of siderophore synthesis genes in Pseudomonas aeruginosa colonies to identify sources and functional roles of cellular heterogeneity.

This study identifies pyoverdines from Pseudomonas spp. as potent antibacterials against human pathogens by inducing iron starvation, showing reduced resistance potential compared to antibiotics.

The paper predicts competitive rank order in a 4-species bacterial community using monoculture growth and supernatant assay data.

This study shows S. aureus rapidly evolves resistance to P. aeruginosa inhibitory molecules through strain-specific mutations in membrane transporters and virulence trait up-regulation.

This study shows that enforced specialization in Pseudomonas aeruginosa leads to mutual cheating rather than division of labour under iron limitation.

The paper shows siderophores can either promote or hinder bacterial invasion depending on their dual role as public good or public bad.

This study shows Pseudomonas aeruginosa cells transiently segregate into low and high receptor expressers to regulate quorum sensing, providing a bet-hedging strategy.

The paper uses microscopy to study siderophore gene expression in Pseudomonas aeruginosa, finding initial heterogeneity that becomes homogenized with increasing cell density and a shift in siderophore usage.

The paper shows that Pseudomonas aeruginosa evolves diverse pyoverdine production strategies in different environments, with hyper-producers favored in high viscosity and iron-rich conditions.

The paper investigates factors driving siderophore-mediated social interactions in Pseudomonas communities, finding phylogenetic relatedness, not geographical distance, primarily determines cooperation and cheating behaviors.

This study shows that deleting the pyoverdine secondary receptor FpvB in Pseudomonas aeruginosa creates a fitter strain that outcompetes wildtype in structured environments under antibiotic stress.

This study combines antivirulence compounds with antibiotics to treat Pseudomonas aeruginosa infections, finding synergistic effects and reduced resistance selection in some cases.

The paper shows that inter-species green-beard cooperation in bacteria is undermined by antagonistic interactions, as Pseudomonas aeruginosa outcompetes Burkholderia cenocepacia despite shared cooperative traits.

The paper uses in vivo microscopy to study Pseudomonas aeruginosa social interactions in C. elegans, finding that non-producers cannot outcompete producers due to spatial segregation.

The paper uses individual-based modeling to show that toxin-mediated policing can enforce cooperation in bacteria under specific conditions, but its evolutionary stability is limited.

This study evaluates the evolutionary robustness of two drugs targeting iron uptake in Pseudomonas aeruginosa, finding that resistance development varies between the drugs.

The paper investigates how environmental factors influence pyoverdine production and competition among Pseudomonas strains in natural communities.