Author

E. Rujas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:deep learning· 1 Approach:graph neural network· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

J.-P. Julien· 3 shared H. Cui· 2 shared K. Muthuraman· 2 shared A. Haller· 1 shared A. Jetha· 1 shared A. Sultana· 1 shared A. Windemuth· 1 shared B. Poon· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

J.-P. Julien

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Antibody avidity and multi-specificity combined to confer protection against SARS-CoV-2 and resilience against viral escape

C. Burn Aschner, K. Muthuraman, I. Kucharska, H. Cui, K. Prieto, M. S. Nair, M. Wang, Y. Huang, N. Christie-Holmes, B. Poon, J. Lam, A. Sultana, R. Kozak, S. Mubareka, J. L. Rubinstein, , J.-P. Julien

This study develops a multimeric antibody platform (Multabody) that enhances neutralization potency and breadth against SARS-CoV-2 and its variants through avidity and multi-specificity.

bioRxiv · Oct 23, 2022 · PreprintImmunology

Dual inhibition of vacuolar ATPase and TMPRSS2 is required for complete blockade of SARS-CoV-2 entry into cells

S. Icho, E. Rujas, K. Muthuraman, J. Tam, H. Liang, S. Harms, M. Liao, D. Falzarano, J.-P. Julien, R. Melnyk

This study identifies bafilomycin A1 as a potent inhibitor of SARS-CoV-2 entry via the endosomal route and shows synergy with TMPRSS2 inhibitors.

bioRxiv · Mar 11, 2022Cell Biology

Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease

M. Sugiyama, H. Cui, D. S. Redka, M. Karimzadeh, E. Rujas, H. Maan, S. Hayat, K. Cheung, R. Misra, J. B. McPhee, R. D. Viirre, A. Haller, R. Botelho, R. Karshafian, S. A. Sabatinos, , C. N. Antonescu

bioRxiv · Apr 13, 2021Cell Biology