R. Rosenzweig

This study identifies a unique chaperoning mechanism in class-A JDPs that recognizes and stabilizes mutant p53, promoting cancer progression by preventing its degradation.

This study reveals the role of UFL1's N-terminal helix in binding UFC1 and ufmylation, uncovering a helix-mediated regulatory mechanism in the E1-E2-E3 cascade.

This study shows DNAJA2 and DNAJB1 prevent tau amyloid formation by binding distinct tau species, while HSPB1 only binds monomers, revealing complementary roles of Hsp40 chaperones in tau aggregation prevention.

This paper identifies the tetrameric structure of the Phosphoprotein (P) as essential for RSV budding and shows its direct interaction with the Matrix (M) protein during assembly.