Author

S. de Seigneux

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Faivre· 2 shared A. P. McMahon· 2 shared D. Legouis· 2 shared J. Pugin· 2 shared K. Koppitch· 2 shared M. Naesens· 2 shared A. Hertig· 1 shared A. Rinaldi· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersPathology

A. Faivre

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2 papers

Recent·Most cited

PathologybioRxivOct 5, 2021

Single-cell profiling in COVID-19 associated acute kidney injury reveals patterns of tubule injury and repair in human

D. Legouis, A. Rinaldi, G. Arnoux…·P. E. Cippa

This study uses single-nucleus RNA sequencing to analyze kidney tubule injury and repair in COVID-19 patients, identifying cell state transitions and reparative mechanisms.

DOI 10.1016/j.isci.2024.109271

humanscRNA-seq

𝕏 PostBluesky

Cell BiologybioRxivOct 16, 2019

Impaired renal gluconeogenesis is a major determinant of acute kidney injury associated mortality

D. Legouis, S.-E. Ricksten, A. Faivre…·S. de Seigneux

This study shows impaired renal gluconeogenesis during AKI contributes to systemic metabolic disturbances and mortality, with thiamine supplementation reducing mortality in critically ill patients.

DOI 10.1038/s42255-020-0238-1

humanmouse

𝕏 PostBluesky