A. P. McMahon

This paper introduces a genetic mouse model for in vivo proximity labeling of the secretome, revealing organ-specific secretory profiles and serum trafficking.

This study uses single-nucleus RNA sequencing to analyze kidney tubule injury and repair in COVID-19 patients, identifying cell state transitions and reparative mechanisms.

The paper spatially maps the human nephrogenic program using single-cell RNA sequencing and generates functional gene-networks to identify developmental disease genes and predict new targets.

This study shows impaired renal gluconeogenesis during AKI contributes to systemic metabolic disturbances and mortality, with thiamine supplementation reducing mortality in critically ill patients.

The paper identifies a late B lymphocyte response linked to renal dysfunction and fibrosis following kidney injury and transplantation.