Cancer BiologybioRxivPreprint
Hypoxic memory of tumor intrinsic type I interferon suppression promotes breast cancer metastasis
O. Iriondo, D. Mecenas, Y. Li…·M. Yu
The paper shows hypoxia induces a long-lasting suppression of type I interferon and antigen presentation in breast cancer cells, enhancing metastasis and being reversible with HDACi and immunotherapy.
DOI 10.1101/2022.05.12.491632