Author

A. Moriarty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. D. Smith· 1 shared A. Dickerson· 1 shared A. Thomas· 1 shared B. A. Benayoun· 1 shared C. Mason· 1 shared C. R. Chin· 1 shared D. Mecenas· 1 shared E. Galkina· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. D. Smith

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2 papers

Recent·Most cited

Neutrophil-specific STAT4 deficiency reduces atherogenesis and improves plaque stability via reduced neutrophil activation and recruitment to aortas.

E. Galkina, W. C. Keeter, A. Moriarty, R. AKers, S. Ma, M. Mussbacher, J. Nadler

This study shows that reducing STAT4 in neutrophils lowers atherosclerosis and improves plaque stability by decreasing neutrophil activation and their migration to aortas.

bioRxiv · Feb 22, 2023 · PreprintImmunology

Hypoxic memory of tumor intrinsic type I interferon suppression promotes breast cancer metastasis

O. Iriondo, D. Mecenas, Y. Li, C. R. Chin, A. Thomas, Y. Amzaleg, A. Moriarty, V. Ortiz, M. MacKay, A. Dickerson, G. Lee, S. Harotoonian, B. A. Benayoun, A. D. Smith, C. Mason, , M. Yu

The paper shows hypoxia induces a long-lasting suppression of type I interferon and antigen presentation in breast cancer cells, enhancing metastasis and being reversible with HDACi and immunotherapy.

bioRxiv · May 12, 2022 · PreprintCancer Biology