C. Mason

Historic breeding practices contribute to germplasm divergence in leaf specialized metabolism and ecophysiology in cultivated sunflower (Helianthus annuus).

This study examines how historical breeding practices in sunflower affect leaf ecophysiology and specialized metabolism by analyzing 288 cultivated lines across heterotic groups.

Supervised Machine Learning Enables Geospatial Microbial Provenance

This study uses supervised machine learning to identify microbial fingerprints in urban and oceanic environments, achieving high accuracy in location classification.

Hypoxic memory of tumor intrinsic type I interferon suppression promotes breast cancer metastasis

The paper shows hypoxia induces a long-lasting suppression of type I interferon and antigen presentation in breast cancer cells, enhancing metastasis and being reversible with HDACi and immunotherapy.

Cross-kingdom metagenomic profiling of Lake Hillier reveals pigment-rich polyextremophiles and wide-ranging metabolic adaptations

This study profiles the metagenome of Lake Hillier to identify pigment-producing microbes and their metabolic adaptations contributing to its pink color.

Screening of Chimeric GAA Variants in a Preclinical Study of Pompe Disease Results in Candidate Vector for Hematopoietic Stem Cell Gene Therapy

This study screens chimeric GAA variants in a preclinical Pompe disease model, identifying a candidate vector for hematopoietic stem cell gene therapy that reduces glycogen accumulation and CNS vacuolation.

Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses

This study shows that Omicron-B.1.1.529 has extensive mutations in Spike that reduce neutralization by antibodies from vaccinated and previously infected individuals, and escape most monoclonal antibodies.

A wipe-based stool collection and preservation kit for microbiome community profiling

This paper introduces and validates a DESS wipe-based method for stool collection and preservation, showing high accuracy and diversity maintenance compared to freezing and commercial kits.

Telomere length dynamics in response to DNA damage in malaria parasites

The paper examines telomere length dynamics in malaria parasites following DNA damage, finding that telomere healing produces excess repeats that later normalize.

Cell-free DNA (cfDNA) and exosome profiling from a year-long humanspaceflight reveals circulating biomarkers

This study profiles cfDNA and exosomes from an astronaut during a year-long spaceflight, identifying increased cf-mtDNA and exosomal brain-derived peptides as potential biomarkers of spaceflight-related stress.

Females and hermaphrodites of the gynodioecious Geranium maculatum respond similarly to soil nutrient availability.

The paper compares growth and physiological responses of female and hermaphrodite Geranium maculatum plants to varying soil nutrient levels, finding similar growth responses but potential differences in chlorophyll content.

Holobiont Urbanism: sampling urban beehives reveals cities' metagenomes

This study uses urban beehives to sample city metagenomes, finding bee debris as the richest substrate, and discusses applications for epidemic surveillance.

The microbiomes of seven lichen genera reveal host specificity, a reduced core community and potential as source of antimicrobials

The paper analyzes the microbiomes of seven lichen genera in Colombian Paramos, revealing host specificity, a core community, and potential antimicrobial compounds.

Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors

This study identifies PGBD5 as an oncogenic DNA transposase in rhabdoid tumors, causing site-specific genomic rearrangements through PSS sequences and end-joining repair.