S. K. Kureel

Low-frequency ultrasound rejuvenates senescent cells by reversing 15 characteristics, including autophagy activation and reduced SASP secretion, improving healthspan in mice.

This study shows that substrate stiffness between 1 and 5 kPa acts as a mechanical switch for hMSC cell cycle regulation via contractile forces, distinct from other cell types.

This paper shows that culturing human mesenchymal stem cells on soft polyacrylamide gel maintains their stemness by delaying senescence compared to traditional tissue culture plates.