Structure-based design of stabilized recombinant influenza neuraminidase tetramers
D. Ellis, J. Lederhofer, O. J. Acton, Y. Tsybovsky, S. Kephart, C. Yap, R. A. Gillespie, A. Creanga, T. Stephens, D. Pettie, M. Murphy, A. J. Borst, Y.-J. Park, K. K. Lee, B. S. Graham, , M. Kanekiyo
This study designs stabilized recombinant influenza neuraminidase tetramers by uncovering structural principles and improving thermal stability and antibody affinity.
bioRxiv · May 17, 2021Microbiology