BiophysicsbioRxivPreprint
Structure of the lysosomal membrane fusion machinery
D. Shvarev, J. Schoppe, C. Koenig…·C. Ungermann
This study determines the structure of HOPS, a lysosomal fusion machinery, revealing its rigid architecture and how it couples membrane tethering with SNARE assembly to facilitate fusion.
DOI 10.1101/2022.05.05.490745