Cancer BiologybioRxiv
Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer
T. Kim, B.-S. Park, S. Heo…·T. Lu
The paper identifies FYN and KDM4 as synergistic targets for enhancing TKI efficacy in triple negative breast cancer through CRISPR screens and mechanistic analysis.
DOI 10.7554/elife.93921.3