Author

S. Heo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Srivastava· 1 shared B.-S. Park· 1 shared C.-K. Lee· 1 shared D. Kim· 1 shared E.-H. Hong· 1 shared H. Jeon· 1 shared H. Jeong· 1 shared H.-J. Ko· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiophysics

A. Srivastava

Author profile →

3 papers

Recent·Most cited

Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer

T. Kim, B.-S. Park, S. Heo, H. Jeon, J. Kim, D. Kim, S. Kook Lee, S.-Y. Jung, S.-Y. Kong, T. Lu

The paper identifies FYN and KDM4 as synergistic targets for enhancing TKI efficacy in triple negative breast cancer through CRISPR screens and mechanistic analysis.

bioRxiv · Nov 8, 2023Cancer Biology

Amelioration of DSS-induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22

S. Kim, E.-H. Hong, C.-K. Lee, Y. Ryu, H. Jeong, S. Heo, J.-j. Lee, H.-J. Ko

This study produces recombinant monomeric human IL-22 and shows it reduces DSS-induced colitis and pro-inflammatory cytokines in mice.

bioRxiv · Nov 4, 2021 · PreprintImmunology

Structure-guided DNA-DNA attraction mediated by divalent cations

A. Srivastava, R. Timsina, S. Heo, S. W. Dewage, S. Kirmizialtin, X. Qui

This study identifies sequence-dependent DNA-DNA condensation mediated by divalent cations, revealing a mechanism involving sequence-enhanced major groove binding.

bioRxiv · Feb 27, 2020Biophysics