Author

P. Chandra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

J. A. Philips· 2 shared A. Banerjee· 1 shared A. Brown· 1 shared A. Irizarry· 1 shared A. Sboner· 1 shared B. Bhinder· 1 shared E. Podaza· 1 shared G. Markowitz· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

J. A. Philips

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Novel co-culture strategies of tumor organoids with autologous T-cells reveal clinically relevant combinations of immune-checkpoint and targeted therapies

E. Podaza, J. Capuano, M. Al Assaad, H.-h. Kuo, G. Markowitz, A. Irizarry, H. Ravichandran, S. Ackermann, T. Kane, J. Manohar, M. Sigouros, J. Moyer, B. Bhinder, P. Chandra, M. Malbari, , M. L. Martin

The paper develops co-culture strategies of tumor organoids with autologous T-cells to screen immune-checkpoint and targeted therapy combinations.

bioRxiv · Jul 5, 2023 · PreprintImmunology

Molecular Basis for Interferon-mediated Pathogen Restriction in Human Cells

S. K. Matta, H. P. Kohio, P. Chandra, A. Brown, J. G. Doench, J. A. Philips, S. Ding, L. D. Sibley

This study identifies RNF213 as essential for IFN-gamma-mediated restriction of intracellular pathogens like Toxoplasma gondii and Mycobacterium tuberculosis through ubiquitination, independent of autophagy.

bioRxiv · Oct 21, 2022 · PreprintMicrobiology

Comprehensive analysis of genomic diversity of SARS-CoV-2 in different geographic regions of India: An endeavour to classify Indian SARS-CoV-2 strains on the basis of co-existing mutations

R. Sarkar, S. Mitra, P. Chandra, P. Saha, A. Banerjee, S. Dutta, M. Chawla-Sarkar

This study analyzes SARS-CoV-2 genomic diversity in India, identifying 33 mutations and classifying strains into 22 groups based on co-existing mutations.

bioRxiv · Jul 14, 2020Microbiology

Fatty acid oxidation impairs macrophage effector functions that control Mycobacterium tuberculosis

P. Chandra, L. He, M. Zimmerman, G. Yang, S. Koster, M. Ouimet, H. Wang, K. J. Moore, V. Dartois, J. D. Schilling, J. A. Philips

This study shows that blocking fatty acid oxidation in macrophages enhances their ability to control Mycobacterium tuberculosis infection by boosting reactive oxygen species and xenophagy.

bioRxiv · Oct 10, 2019 · PreprintMicrobiology