Author

S. Lindquist

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Organism:yeast· 1

Frequent Co-Authors

P. Tsvetkov· 2 shared Z. Brune· 2 shared A. Detappe· 1 shared A. Tsherniak· 1 shared C. Kayatekin· 1 shared D. Pincus· 1 shared E. Hallacli· 1 shared G. A. Newby· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

P. Tsvetkov

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Author profile →

2 papers

Recent·Most cited

Transient Hsp90 suppression promotes a heritable change in protein translation

P. Tsvetkov, Z. Brune, T. J. Eisen, S. Heinrich, G. A. Newby, E. Hallacli, C. Kayatekin, D. Pincus, S. Lindquist

The paper shows that transient Hsp90 suppression causes a heritable change in protein translation that persists across generations.

bioRxiv · Jul 10, 2018Cell Biology

Inhibition of mitochondrial ferredoxin 1 (FDX1) prevents adaptation to proteotoxic stress

P. Tsvetkov, A. Detappe, K. Cai, H. R. Keys, Z. Brune, W. Ying, P. Thiru, M. Reidy, G. Kugener, A. Tsherniak, S. Santagata, L. Whitesell, J. L. Markley, I. M. Ghobrial, S. Lindquist

This study identifies FDX1 inhibition as a strategy to prevent proteasome inhibitor resistance in cancer by targeting mitochondrial Fe-S cluster biosynthesis.

bioRxiv · Mar 24, 2018Cancer Biology