MBNL1 and RBFOX1 co-regulate alternative splicing events transcriptome-wide through a conserved buffering mechanism
J. A. Berglund, M. Hale, J. A. Ellis, R. Meng, S. McDaniel, A. Mahady, S. Wagner, J. Richardson, O. McConnell, E. T. Wang
This study identifies a conserved buffering mechanism where MBNL1 and RBFOX1 co-regulate alternative splicing by overlapping RNA motifs, reducing the range of splicing outcomes.
bioRxiv · Apr 20, 2021 · PreprintBiochemistry