Author

S. Minguet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A.-M. Schaffer· 2 shared G. J. Fiala· 2 shared K. Raute· 2 shared L. A. Herr· 2 shared W. W. Schamel· 2 shared A. Plach· 1 shared B. Salzer· 1 shared D. H. Busch· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

A.-M. Schaffer

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation

T. Peters, V. Muehlgrabner, R. M. H. Velasco Cardenas, R. Platzer, J. Gohring, B. Salzer, A. Plach, M. Hoehrhan, I. Doel-Perez, V. D. R. Goncalves, J. S. Farfan, M. Lehner, H. Stockinger, W. W. Schamel, K. Schober, , J. B. Huppa

This study shows TCR/CD3-based synthetic antigen receptors (TCC) have superior antigen sensitivity and activation fidelity compared to second-generation CARs.

bioRxiv · Mar 16, 2023 · PreprintImmunology

Kidins220 promotes thymic iNKT cell development by reducing TCR signals, but enhances TCR signals in splenic iNKT cells

L. A. Herr, G. J. Fiala, A.-M. Schaffer, K. Raute, R. M.-H. Velasco Cardenas, J. F. Hummel, K. Ebert, Y. Tanriver, S. Minguet, W. W. Schamel

This study shows Kidins220 modulates TCR signaling in thymic and splenic iNKT cells, promoting development in the thymus by reducing TCR signals but enhancing TCR signals in the periphery.

bioRxiv · Apr 5, 2022 · PreprintImmunology

Kidins220 regulates the development of B cells bearing the {lambda} light chain

A.-M. Schaffer, G. J. Fiala, M. Hils, E. Natali, L. Babrak, L. A. Herr, M. Rizzi, E. Miho, W. Schamel, S. Minguet

This study shows Kidins220 regulates λLC B cell development by supporting precursor survival and optimizing pre-BCR/BCR signaling for λLC locus opening and recombination.

bioRxiv · Apr 4, 2022Immunology

Breast cancer stem cell-derived tumors escape from γδ T cell immunosurveillance in vivo by modulating γδ T cell ligands

K. Raute, J. Strietz, G. Andrieux, O. S. Thomas, K. M. Kistner, M. Zintchenko, P. Aichele, H. Zhou, W. Weber, M. Boerries, M. Swamy, J. Maurer, S. Minguet

This study shows that breast cancer stem cells escape γδ T cell immunosurveillance by losing key ligands and antigens, and that this escape can be reversed with Zoledronate or IFN- treatment.

bioRxiv · Apr 4, 2022Immunology