Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
A. Tasegian, D. Dikovskaya, M. Scott, T. Helps, T. Meus, M. H. McLean, M. Swamy
The paper investigates the role of LRRK2 in lysozyme expression in Paneth cells and finds that LRRK2 is not required for lysozyme expression in the murine gut and is not expressed in Paneth cells.
bioRxiv · Mar 7, 2024Physiology
A. S. Chawla, H. J. Watt, S. A. Schattgen, N. Skariah, I. Saha, K. Warrick, M. Ogawa, F. Lamoliatte, J. Strid, A. Copland, S. Pryde, E. Knatko, K. D. Rasmussen, K. Kikuchi, P. G. Thomas, , M. Swamy
The paper identifies a conserved mechanism, RePrESS, by which autoreactive innate-like T cells maintain tolerance through rewiring of the TCR signalosome.
bioRxiv · Sep 1, 2023 · PreprintImmunology
A. J. Brenes, J. L. Hukelmann, L. Spinelli, A. J. M. Howden, J. M. Marchingo, L. V. Sinclair, C. Rollings, O. J. James, I. R. Phair, S. P. Matthews, S. H. Ross, S. C. Arthur, M. Swamy, D. K. Finlay, A. I. I. Lamond, D. A. Cantrell
The paper introduces ImmPRes, a proteomic resource integrating mass-spectrometry data from murine hematopoietic cells to study immune activation and signaling.
bioRxiv · Aug 29, 2022Immunology
K. Raute, J. Strietz, G. Andrieux, O. S. Thomas, K. M. Kistner, M. Zintchenko, P. Aichele, H. Zhou, W. Weber, M. Boerries, M. Swamy, J. Maurer, S. Minguet
This study shows that breast cancer stem cells escape γδ T cell immunosurveillance by losing key ligands and antigens, and that this escape can be reversed with Zoledronate or IFN- treatment.
bioRxiv · Apr 4, 2022Immunology
A. S. Chawla, M. Vandereyken, M. Arias, L. Santiago, D. Dikovskaya, C. Nguyen, N. Skariah, N. Wenner, N. Golovchenko, S. Thomson, E. Ondari, M. Garzon-Tituana, C. J. Anderson, M. Bergkessel, J. C. D. Hinton, , M. Swamy
This study shows that granzymes A and B use distinct cell death pathways to protect against intestinal Salmonella infection by balancing bacterial growth and translocation.
bioRxiv · Nov 7, 2021Immunology
A. J. Brenes, M. Vandereyken, O. J. James, J. Hukelmann, L. Spinelli, A. I. Lamond, M. Swamy
The paper uses proteomic analysis to show that the gut environment, not developmental origin, shapes the functional properties of intestinal intraepithelial T lymphocytes.
bioRxiv · Mar 15, 2021Immunology
O. J. James, M. Vandereyken, J. M. Marchingo, F. Singh, A. G. Love, M. Swamy
The paper uses proteomics to identify PIM kinases as critical regulators of IL-15-driven activation in intestinal intraepithelial lymphocytes, linking them to Coeliac disease.
bioRxiv · Mar 27, 2020Immunology
Y. Chen, I. P. Newton, M. Vandereyken, I. Moraga, I. Nathke, M. Swamy
This study shows that loss of Apc function in intestinal epithelial cells reduces IL-22 receptor expression and STAT3 activation, leading to resistance to IL-22 and increased genetic instability.
bioRxiv · Dec 1, 2018Immunology