ImmunologybioRxivPreprint
Long-term retention of antigens in germinal centres is controlled by the spatial organisation of the follicular dendritic cell network
A. Martinez-Riano, S. Wang, S. Boeing…·P. Tolar
The paper shows that follicular dendritic cells (FDCs) in germinal centers (GCs) have distinct spatial organization that controls antigen retention, with central FDCs acting as long-term antigen reservoirs.
DOI 10.1101/2022.09.06.506650