S. Shinkai

This study shows that CENP-C oligomerization is essential for centromere function by organizing centromeric chromatin and maintaining kinetochore assembly in vertebrates.

The paper tracks Nanog and Oct4 in mouse embryonic stem cells to study their roles in pluripotency, finding that Nanog interacts longer with targets during differentiation, suggesting a feedback mechanism.

This paper introduces a microrheology method for Hi-C data to analyze the dynamic 3D genome organization, revealing rigid TAD boundaries and liquid-like inter-compartment interactions during neural differentiation.

This paper uses mathematical modeling to link chromatin domain dynamics and organization by analyzing nucleosome movement in living human cells.