BioengineeringbioRxivPreprint
Efficient Development of Platform Cell Lines Using CRISPR-Cas9 and Transcriptomics Analysis
A. T.-J. Kwon, K. Mohri, S. Takizawa…·E. Arner
The paper develops CRISPR-Cas9 mutants of U87MG cells to create platform cell lines for drug testing, finding that transcriptomic analysis helps identify clones with minimal phenotypic divergence from wild type.
DOI 10.1101/2020.09.16.299248