J. Duerr

Ileal mucus viscoelastic properties differ in Crohns disease

This study examines ileal mucus viscoelastic properties in Crohn's disease patients and controls, finding significant differences in viscoelasticity and mesh size.

Functional lung imaging identifies peripheral ventilation changes in mice with muco-obstructive lung disease

This study uses X-ray Velocimetry to identify peripheral ventilation changes in a mouse model of muco-obstructive lung disease.

Reflection confocal microscopy for quantitative assessment of airway surface liquid dysregulation and pharmacological rescue in cystic fibrosis under near-physiological conditions

This paper introduces confocal reflection microscopy as a method to measure airway surface liquid height in cystic fibrosis models without perturbing the ASL, showing it is sensitive to detect ASL changes and therapeutic responses.

Longitudinal Micro-Computed Tomography Detects Onset and Progression of Pulmonary Fibrosis in Conditional Nedd4-2 Deficient Mice

This study uses longitudinal micro-CT to detect and quantify the onset and progression of IPF-like lung disease in Nedd4-2-/- mice.

Dextromethorphan inhibits collagen transport in the endoplasmic reticulum eliciting an anti-fibrotic response in ex-vivo and in vitro models of pulmonary fibrosis

This study shows Dextromethorphan reduces collagen deposition in fibrotic models by inhibiting collagen trafficking in the endoplasmic reticulum.

Light dynamically regulates growth rate and cellular organisation of the Arabidopsis root meristem.

The paper develops a method to quantify 3D cell parameters in Arabidopsis root tips under light/dark conditions, revealing differences in meristematic zone length across cell layers.