Author

S. V. Zaitsev

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

D. B. Cines· 2 shared M. Poncz· 2 shared V. Stepanova· 2 shared A. Saiyed· 1 shared B. J. Buckley· 1 shared B. Piper· 1 shared D. Goncharov· 1 shared D. Lin· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

D. B. Cines

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Author profile →

2 papers

Recent·Most cited

Cell BiologybioRxivPreprintDec 5, 2023

Packaging of supplemented urokinase into naked alpha-granules of in vitro-grown megakaryocytes for targeted therapeutic delivery

M. Poncz, S. V. Zaitsev, H. Ahn…·V. Stepanova

The paper demonstrates that in vitro-grown megakaryocytes can store exogenous uPA in alpha-granules, which can be used to generate anti-thrombotic human platelets that lyse nascent thrombi in a mouse model.

DOI 10.1101/2023.12.05.570278

mouseproteomics

𝕏 PostBluesky

Cell BiologybioRxivSep 21, 2023

PAI-1 Deficiency Drives Pulmonary Vascular Smooth Muscle Remodeling and Pulmonary Hy-pertension

T. V. Kudryashova, S. V. Zaitsev, L. Jiang…·V. Stepanova

This study shows PAI-1 deficiency in PASMC promotes pulmonary vascular remodeling and hypertension by enhancing uPA activity, leading to cell proliferation and reduced apoptosis.

DOI 10.1152/ajplung.00110.2024

mousehuman

𝕏 PostBluesky