H. Ahn

Studies of infused megakaryocytes into mice support a ''catch-and release'' model of pulmonary-centric thrombopoiesis

The paper shows that megakaryocytes are entrapped in the lungs, release cytoplasmic fragments, and undergo platelet formation, supporting a pulmonary-centric 'catch-and-release' model of thrombopoiesis.

A cryopreservation strategy for myoblast storage in paper-based scaffolds for inter-laboratory studies of skeletal muscle health

This paper develops a cryopreservation method for myoblasts in paper-based scaffolds, enabling inter-laboratory studies of skeletal muscle health.

Packaging of supplemented urokinase into naked alpha-granules of in vitro-grown megakaryocytes for targeted therapeutic delivery

The paper demonstrates that in vitro-grown megakaryocytes can store exogenous uPA in alpha-granules, which can be used to generate anti-thrombotic human platelets that lyse nascent thrombi in a mouse model.

Culture substrate stiffness impacts human myoblast contractility-dependent proliferation and nuclear envelope wrinkling

This study shows that fibronectin promotes stronger stiffness-dependent responses in human myoblasts compared to laminin and collagen, with softer substrates increasing nuclear wrinkling linked to proliferation.

Class-Controlled Copy-Paste Based Cell Segmentation for CoNIC Challenge

The paper introduces a class-controlled copy-paste augmentation method to address class imbalance in histopathology cell segmentation, improving metrics for underrepresented classes.

Evaluation of biodiversity in estuaries using environmental DNA metabarcoding

The paper evaluates biodiversity in estuaries using environmental DNA metabarcoding, finding higher diversity in less developed rivers and species composition reflecting ecological and environmental factors.

Development of Systemic Immune Dysregulation in a Rat Trauma Model with Biomaterial-Associated Infection

This study investigates the systemic immune response to orthopedic biomaterial-associated infection in rats, finding long-term immune dysregulation and altered cytokine responses.

Computational and experimental evidence to the permeability of withanolides across the normal cell membrane

This study uses computational simulations and experiments to show that withaferin-A, but not withanone, can cross cell membranes due to differences in their molecular interactions with the membrane.

A 96-well culture platform enables longitudinal analyses of engineered human skeletal muscle microtissue strength

The paper introduces a 96-well platform for culturing human skeletal muscle microtissues to study their strength and response to drugs over time.

A three-dimensional culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction and disease modeling

This paper introduces a 3D co-culture model of human skeletal muscle and motor neurons to study adult neuromuscular junction development and disease, showing increased receptor upregulation and disease modeling capability.