Author

S. Wigmore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Adair· 1 shared A. Christie· 1 shared A. Meynert· 1 shared A. Stockman· 1 shared B. Stutchfield· 1 shared C. Hay· 1 shared D. A. Hume· 1 shared D. J. Mole· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperPathology

A. Adair

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In vivo modelling of patient genetic heterogeneity identifies concurrent Wnt and PI3K activity as a potent driver of invasive cholangiocarcinoma growth.

N. Younger, M. Wilson, E. Jarman, A. Meynert, G. Grimes, K. Gournopanos, S. Waddell, P. Tennant, D. Wilson, R. Guest, S. Wigmore, J. C. Acosta, T. J. Kendall, M. Taylor, D. Sproul, , L. Boulter

This study identifies concurrent Wnt and PI3K activity as drivers of invasive cholangiocarcinoma growth and shows that their co-inhibition slows tumor growth in vivo.

bioRxiv · Jul 5, 2021 · PreprintCancer Biology

Serum CSF1 levels are elevated in patients following partial hepatectomy and acetaminophen induced acute liver failure: Reanalysis of previous data

B. Stutchfield, P. Starkey Lewis, S. Wigmore, K. Simpson, D. A. Hume, S. J. Forbes

This study reanalyzes previous data showing elevated serum CSF1 levels after partial hepatectomy and in ALF patients, with higher levels in non-survivors.

bioRxiv · Apr 2, 2021 · PreprintImmunology

Patterns of recurrence after curative-intent surgery for pancreas cancer reinforce the importance of locoregional control and adjuvant chemotherapy.

R. Munir, K. Soreide, R. Ravindran, J. J. Powell, E. Harrison, A. Adair, S. Wigmore, R. Parks, O. J. Garden, L. Kirkpatrick, L. R. Wall, A. Christie, I. Penman, N. McAvoy, V. Save, , D. J. Mole

This study examines recurrence patterns in pancreas cancer patients after surgery, finding that locoregional recurrence is common and linked to R+ resection and venous invasion, with adjuvant chemotherapy improving survival.

bioRxiv · Oct 18, 2018 · PreprintPathology