Computation-aided Design of Rod-Shaped Janus Base Nanopieces for Improved Tissue Penetration and Therapeutics Delivery
J. Lee, W. Zhang, D. Nguyen, L. Zhou, J. Amengual, J. Zhai, T. Cote, M. Landolina, E. Ahmadi, N. Mishra, H. Yu, M.-P. Nieh, K. Wang, Y. Li, Y. Chen
This study develops rod-shaped Janus base nanopieces for improved tissue penetration and therapeutics delivery, showing better efficacy than spherical lipid nanoparticles in ovarian cancer models.
bioRxiv · Jan 24, 2024Bioengineering