Author

J. Amengual

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

E. A. Fisher· 2 shared A. Alay· 1 shared A. Albakri· 1 shared A. Blanco· 1 shared A. Esteve-Codina· 1 shared A. M. Valverde· 1 shared A. Sanchez· 1 shared B. Herrera· 1 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiochemistry

E. A. Fisher

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Computation-aided Design of Rod-Shaped Janus Base Nanopieces for Improved Tissue Penetration and Therapeutics Delivery

J. Lee, W. Zhang, D. Nguyen, L. Zhou, J. Amengual, J. Zhai, T. Cote, M. Landolina, E. Ahmadi, N. Mishra, H. Yu, M.-P. Nieh, K. Wang, Y. Li, Y. Chen

This study develops rod-shaped Janus base nanopieces for improved tissue penetration and therapeutics delivery, showing better efficacy than spherical lipid nanoparticles in ovarian cancer models.

bioRxiv · Jan 24, 2024Bioengineering

FITM2 deficiency results in ER lipid accumulation, ER stress, reduced apolipoprotein B lipidation, and VLDL triglyceride secretion in vitro and in mouse liver

H. Wang, C. Nikain, J. Amengual, M. La Forest, Y. Yu, M. C. Wang, R. Watts, R. Lehner, Y. Qiu, M. Cai, I. J. Kurland, I. J. Goldberg, S. Rajan, M. M. Hussain, J. L. Brodsky, E. A. Fisher

This study shows FITM2 deficiency reduces VLDL triglyceride secretion and causes ER stress and lipid accumulation in liver cells and mice.

bioRxiv · Dec 5, 2023 · PreprintBiochemistry

The hepatocyte Epidermal Growth Factor Receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche

E. Gonzalez-Sanchez, J. Vaquero, D. Caballero-Diaz, J. Grzelak, N. P. Fuste, E. Bertran, J. Amengual, J. Garcia-Saez, B. Martin-Mur, M. Gut, A. Esteve-Codina, A. Alay, C. Coulouarn, S. Calero, P. Valdecantos, , I. Fabregat

This study shows that inhibiting EGFR in hepatocytes reduces liver fibrosis by altering immune cell populations and molecular mechanisms involved in inflammation and fibrogenesis.

bioRxiv · Nov 3, 2023Pathology

β-carotene accelerates the resolution of atherosclerosis in mice

I. Pinos, J. Coronel, A. Albakri, A. Blanco, P. McQueen, D. Molina, J. Sim, E. A. Fisher, J. Amengual

This study shows that β-carotene accelerates atherosclerosis resolution in mice without affecting body weight or plasma lipid levels.

bioRxiv · Mar 7, 2023Immunology