Thyroid Hormone Suppresses Medulloblastoma Progression Through Promoting Terminal Differentiation of Tumor Cells
Z. Yang, Y. Yang, S. A. Valdes-Rives, Q. Liu, Y. Li, J. Tan, Y. Tan, C. A. Koch, Y. Rong, S. R. Houser, S. Wei, K. Cai, S.-y. Cheng, T. Curran, R. Wechsler-Reya
This study shows thyroid hormone promotes differentiation of medulloblastoma cells, reducing tumor growth by reversing EZH2-mediated repression of NeuroD1.
bioRxiv · Feb 13, 2024Cancer Biology