Author

T. Doyle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Zoology· 2 Cancer Biology· 1 Evolutionary Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Approach:benchmark study· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

K. Wotton· 2 shared R. Massy· 2 shared S. Weston· 2 shared A. B. Porter· 1 shared A. E. Dulcey· 1 shared A. Hawkins-Daarud· 1 shared A. N. Nilson· 1 shared B. R. Bendok· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersZoology

K. Wotton

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The most remarkable migrants - systematic analysis of the Western European insect flyway at a Pyrenean mountain pass

W. L. Hawkes, T. Doyle, R. Massy, S. Weston, K. Davies, E. Cornelius, C. Collier, J. Chapman, D. Reynolds, K. Wotton

The paper systematically monitors insect migration at a Pyrenean mountain pass, finding a large annual insect flow influenced by environmental factors and estimating a significant bioflow across the mountain range.

bioRxiv · Jul 17, 2023Zoology

Identification and Characterization of ML321: a Novel and Highly Selective D2 Dopamine Receptor Antagonist with Efficacy in Animal Models that Predict Atypical Antipsychotic Activity

R. B. Free, A. N. Nilson, N. M. Boldizsar, T. Doyle, R. M. Rodriguiz, V. M. Pogorelov, M. Machino, K. H. Lee, J. W. Bertz, J. Xu, H. D. Lim, A. E. Dulcey, R. H. Mach, J. H. Woods, J. R. Lane, , D. R. Sibley

This paper develops ML321, a highly selective D2 dopamine receptor antagonist, showing efficacy in animal models predictive of atypical antipsychotic activity with fewer side effects.

bioRxiv · Nov 14, 2022Pharmacology & Toxicology

Migratory hoverflies orientate north during spring migration

W. Hawkes, S. Weston, H. Cook, T. Doyle, R. Massy, E. Jimenez-Guri, R. Wotton Jimenez, K. Wotton

The paper provides ground confirmation that spring migratory hoverflies have an innate northward orientation, observed during their arrival in the UK.

bioRxiv · Aug 8, 2022 · PreprintZoology

The genomic basis of evolved virus resistance is dependent on environmental resources

K. Roberts, S. Meaden, S. Sharpe, S. Kay, T. Doyle, D. Wilson, L. J. Bartlett, S. Paterson, M. Boots

This study identifies genomic mechanisms of virus resistance in a lepidopteran pest, showing that resistance evolves differently under varying nutritional conditions and is linked to metabolic, immune, or cytoskeleton pathways.

bioRxiv · Jun 11, 2019 · PreprintEvolutionary Biology

Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma

S. C. Massey, H. White, P. Whitmire, T. Doyle, S. K. Johnston, K. W. Singleton, P. R. Jackson, A. Hawkins-Daarud, B. R. Bendok, A. B. Porter, S. Vora, J. N. Sarkaria, M. M. Mrugala, K. R. Swanson

The paper uses image-based metrics to predict TMZ response in GBM patients, finding that less invasive tumors show greater volumetric response and improved survival.

bioRxiv · Jan 2, 2019Cancer Biology