S. Vora

Mechanism by which Aurora B inhibitors promotes RB and p53-dependent senescence.

This study investigates how Aurora B inhibitors induce polyploidy and shows that higher ploidy states reduce long-term proliferative potential in cells with functional RB and p53.

Heterozygous mutation of Vegfr3 decreases renal lymphatics but is dispensable for renal function

This study shows that heterozygous Vegfr3 mutation reduces renal lymphatics but does not impair renal function or histology, even after cisplatin injury.

Light-sheet microscopy with isotropic, sub-micron resolution and solvent-independent large-scale imaging

This paper introduces ctASLM, a light-sheet microscopy technique with sub-micron isotropic resolution and large-scale imaging, enabling automated cell and subcellular feature detection in cleared tissues.

Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma

The paper uses image-based metrics to predict TMZ response in GBM patients, finding that less invasive tumors show greater volumetric response and improved survival.

Sex-specific impact of patterns of imageable tumor growth on survival of primary glioblastoma patients

This study identifies sex-specific predictors of survival in glioblastoma patients using MR imaging and clinical data.