T. K. Anderson

This study shows that reassorting the nucleoprotein gene in H3 influenza A viruses improved transmissibility in swine, but transmission efficiency depends on multiple genes.

This paper determines the structure of an alphacoronavirus polymerase complex and identifies conserved cofactor interactions important for antiviral drug development.

This study shows that pdm09 H1N1 influenza viruses from humans can persist in swine, evolve, and transmit back to humans, increasing pandemic risk.

This study characterizes the genetic and antigenic diversity of N1 neuraminidase in IAV from North American swine over a century, identifying clades, reassortment events, and antigenic drift patterns.

The paper assesses the zoonotic risk of swine H1 influenza A viruses by evaluating their cross-reactivity to human vaccine antisera and transmission efficiency in a pig-to-ferret model.

PARNAS selects representative taxa from large phylogenies to cover diversity efficiently, applied to influenza A virus data to inform vaccine design.

This study assesses the antigenic and genetic diversity of swine H1 influenza A viruses in North America to evaluate pandemic risk.

The paper tracks the resurgence of H3 influenza A virus clade C-IVA in US swine, identifying genetic and antigenic factors linked to its increased detection frequency.

This study determines the solution structure of SARS-CoV-2 nsp7 at pH 7.0 using NMR spectroscopy and identifies pH-dependent structural changes in the protein.

RF-Net 2 improves virus reassortment and hybridization network inference by handling more reticulations and providing error correction, validated on influenza A virus data.

This paper evaluates nucleotide analogues as inhibitors of SARS-CoV and SARS-CoV-2 RdRp, identifying those that terminate RNA synthesis and resist viral exonuclease activity.

The paper shows that the triphosphates of tenofovir and emtricitabine inhibit SARS-CoV-2 RNA-dependent RNA polymerase, suggesting potential use of DESCOVY and TRUVADA as PrEP for COVID-19.

This study shows that three nucleotide analogues inhibit SARS-CoV-2 polymerase by being incorporated and blocking further RNA synthesis.

This study shows urbanization affects parasite communities in estuarine fish by altering physicochemical factors and landscape structure, with greater impacts on indirect life-cycle parasites.

This paper introduces RF-Net, a method to reconstruct reticulation networks from error-prone input trees, demonstrating its ability to identify reassortment in influenza A viruses.

The paper describes using field-derived nanopore sequencing to identify a novel swine influenza A virus that posed a pandemic risk, leading to the development of a vaccine candidate and real-time public health response.