T. M. Tomasiak

This study determines the structure of dephosphorylated Ycf1 using cryo-EM, revealing an ordered R-domain topology that mediates autoinhibition and provides insights into its phosphorylation-dependent activation mechanism.

This study presents cryo-EM structures of Ycf1 showing how phosphorylation of the regulatory domain modulates its interaction with NBD1 and affects ATPase activity.

Cryo-EM and EPR analysis reveal cooperative substrate binding in BmrCD in an architecture primed for transport.

This study investigates how the peptide sensor motif in TmrAB coordinates conformational changes during ATP-dependent transport, showing it stabilizes the outward-facing state.