Author

T. Mills

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

E. Y. Faraoni· 2 shared H. K. Eltzschig· 2 shared A. Akimzhanov· 1 shared A. Mohammed· 1 shared B. J. O'Brien· 1 shared B. Shayahati· 1 shared C. J. Wray· 1 shared D. Bar-Sagi· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

E. Y. Faraoni

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CD73 generated extracellular adenosine promotes resolution of neutrophil-mediated tissue injury and restrains metaplasia in pancreatitis

B. J. O'Brien, E. Y. Faraoni, L. N. Strickland, Z. Ma, V. Y. Mota, S. Y. Mota, X. Chen, T. Mills, H. K. Eltzschig, K. E. DelGiorno, J. M. Bailey-Lundberg

This study shows CD73-generated adenosine reduces neutrophil-driven tissue damage and metaplasia in pancreatitis by promoting inflammation resolution.

bioRxiv · Sep 17, 2022Immunology

Pancreatic cancer ductal cell of origin drives CD73-dependent generation of immunosuppressive adenosine

K. Singh, E. Y. Faraoni, Y. Dai, V. Chandra, E. Vucic, T. Mills, M. Pruski, T. Clark, G. Van Buren, N. C. Thosani, J. S. Bynon, C. J. Wray, D. Bar-Sagi, K. L. Poulsen, L. A. Vornik, , J. Bailey Lundberg

This study identifies CD73 as a key driver of immunosuppression in pancreatic ductal adenocarcinoma, showing its role in adenosine generation and tumor progression.

bioRxiv · Nov 29, 2021 · PreprintCancer Biology

Calcium-dependent protein acyltransferase DHHC21 controls activation of CD4+ T cells

B. Shayahati, Y. Fan, S. West, R. Tewari, J. Ko, T. Mills, D. Boehning, A. Akimzhanov

This study identifies DHHC21 as a calcium/calmodulin-dependent enzyme critical for CD4+ T cell activation and differentiation through S-acylation of signaling proteins.

bioRxiv · Sep 1, 2020Immunology