Author

T. Soga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

T. Ishikawa· 2 shared A. De Sciscio· 1 shared A. Okamoto· 1 shared A. Parrish· 1 shared A. Steimle· 1 shared C. G. Proud· 1 shared C. Yamauchi· 1 shared C. Zorbas· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

T. Ishikawa

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Gut microbiome-based prediction of autoimmune neuroinflammation

A. Steimle, M. Neumann, E. Grant, S. Willieme, A. De Sciscio, A. Parrish, M. Ollert, E. Miyauchi, T. Soga, S. Fukuda, H. Ohno, M. S. Desai

The paper identifies a microbial risk factor for autoimmune neuroinflammation by analyzing microbiota compositions and host immune responses in a mouse model of multiple sclerosis.

bioRxiv · Apr 14, 2023 · PreprintMicrobiology

Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via PDH regulation

T. Ikizawa, K. Ikeda, M. Arita, S. Kitajima, T. Soga, H. Ichijo, I. Naguro

The paper shows hyperosmotic stress triggers rapid metabolic changes in cells through mitochondrial PDH regulation, maintaining ATP levels and survival.

bioRxiv · Jun 29, 2022 · PreprintCell Biology

Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

M. Pan, C. Zorbas, M. Sugaya, K. Ishiguro, M. Kato, M. Nishida, H. Zhang, M. M. Candeias, A. Okamoto, T. Ishikawa, T. Soga, H. Aburatani, J. Sakai, Y. Matsumura, T. Suzuki, , T. Osawa

The paper shows that glutamine deficiency in cancer cells prevents p53 activation by rRNA synthesis inhibitors, promoting survival during nutrient stress.

bioRxiv · Dec 3, 2021 · PreprintCancer Biology

HSD11β1 promotes EMT-mediated breast cancer metastasis

J. Nakayama, T. Ishikawa, T. Nishimura, S. Yamanaka, N. Gotoh, C. Yamauchi, T. Onishi, T. Soga, S. Fujii, H. Makinoshima

This study identifies HSD11β1 as a promoter of breast cancer metastasis via EMT induction and shows that targeting HSD11β1 could suppress metastasis.

bioRxiv · Sep 27, 2021 · PreprintCancer Biology

Thiazoline-related TRPA1 agonist odorants orchestrate survival fate in mice

T. Matsuo, T. Isosaka, L. Tang, T. Soga, R. Kobayakawa, K. Kobayakawa

The paper shows that thiazoline-related fear odors induce hypothermia and metabolic changes in mice, enhancing survival in hypoxic conditions through immune and metabolic shifts.

bioRxiv · May 17, 2020 · PreprintPhysiology