Author

U. S. Jhala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Gorantla· 1 shared A. R. Harrington· 1 shared B. R. Cross· 1 shared C. M. Metallo· 1 shared E. Hao· 1 shared F. Liu· 1 shared F. Mulas· 1 shared J. Chiou· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. Gorantla

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 9, 2022

TRB3 augments IL1β-TLR4 signaling by engaging Flightless-homolog 1.

S. Gonuguntla, R. K. Humphrey, A. Gorantla…·U. S. Jhala

This study shows TRB3 enhances IL1β-TLR4 signaling by interacting with Fli1 to release MyD88, promoting proinflammatory responses in beta cells.

DOI 10.1101/2022.10.09.511391

mouseexperimental assay

𝕏 PostBluesky

PhysiologybioRxivAug 21, 2019

Nutrient regulation of the islet epigenome controls adaptive insulin secretion

M. Wortham, F. Liu, J. Y. Fleischman…·M. Sander

This study shows that nutrient-stimulated histone acetylation regulates the islet epigenome to control adaptive insulin secretion, with Lsd1 playing a key role in this process.

DOI 10.1172/jci165208

𝕏 PostBluesky