Cancer BiologybioRxivPreprint
Enhancing radiotherapy response via intratumoral injection of the TLR9 agonist CpG to stimulate CD8 T cells in an autochthonous mouse model of sarcoma
C. Su, C. L. Kent, M. Pierpoint…·D. G. Kirsch
This study shows that combining radiotherapy with CpG, a TLR9 agonist, enhances tumor response in a mouse sarcoma model by boosting CD8 T cell activity.
DOI 10.1101/2024.01.03.573968