V. Tiwari

Fractal Dimension and Lacunarity Measures of Glioma Subcomponents Provide a Quantitative Platform Discriminative of IDH Status: A Radiogenomics Approach in Gliomas

This paper uses fractal dimension and lacunarity from MRI to distinguish IDH status in gliomas, finding higher fractality in IDH wildtype enhancing subcomponents and associations with survival.

Insights into the Interactions of Peptides with Monolayer-Protected Metal Nanoclusters

This study uses molecular dynamics simulations to examine how melittin interacts with gold-based MPCs, revealing hydrogen bonding and electrostatic interactions that stabilize the peptide on the nanocluster surface.

The degree of polymerization and sulfation patterns in heparan sulfate are critical determinants of cytomegalovirus entry into host cells

Ligand-induced motions in pentameric ligand-gated ion channels revealed by EPR spectroscopy

This study uses EPR spectroscopy to reveal ligand-induced structural changes in the extracellular domain of GLIC, showing inward motions associated with agonist-induced closed pre-activated states.

Preferential recognition and antagonism of SARS-CoV-2 spike glycoprotein binding to 3-O-sulfated heparan sulfate

This study shows 3-O-sulfated heparan sulfate enhances SARS-CoV-2 spike protein-mediated cell fusion, which can be blocked by a synthetic small molecule.

Mass cytometry and artificial intelligence define CD169 as a specific marker of SARS-CoV2-induced acute respiratory distress syndrome

The paper identifies a specific immune signature in COVID-19-associated ARDS using mass cytometry and AI, showing it differs from other ARDS causes and is linked to adverse ICU outcomes.

Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling

This study shows that Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis via NAD+ signaling, with NAD+ supplementation improving lifespan and healthspan in CS nematodes.