Author

W. Frigui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Assay:imaging· 1

Frequent Co-Authors

R. Brosch· 3 shared A. Pawlik· 2 shared F. Sayes· 2 shared L. Majlessi· 2 shared L. S. Ates· 2 shared A. Danckaert· 1 shared A. Giraud-Gatineau· 1 shared A. Mai· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

R. Brosch

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A marine sponge-associated mycobacterium closely related to Mycobacterium tuberculosis

S. J. Pidot, S. Klatt, L. S. Ates, W. Frigui, F. Sayes, L. Majlessi, H. Izumi, I. R. Monk, J. L. Porter, V. Bennett-Wood, T. Seemann, A. Otter, G. Taiaroa, G. M. Cook, N. West, , T. P. Stinear

This paper describes the discovery of a marine sponge-associated mycobacterium closely related to M. tuberculosis, which shares virulence factors but lacks virulence in mice.

bioRxiv · Jan 23, 2024 · PreprintMicrobiology

An oxadiazole-based compound potentiates anti- tuberculosis treatment by increasing host resistance via zinc poisoning

A. Maure, E. Lawaree, F. Fiorentino, A. Pawlik, S. Gona, A. Giraud-Gatineau, M. J. G. Eldridge, A. Danckaert, D. Hardy, W. Frigui, C. Keck, N. Aulner, A. Mai, M. Hamon, L. B. Barreiro, , L. Tailleux

The paper identifies oxadiazole-based compounds that enhance anti-tuberculosis treatment by increasing host resistance through zinc poisoning of Mycobacterium tuberculosis.

bioRxiv · Jul 21, 2023 · PreprintMicrobiology

De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

T. Laval, L. Pedro-Cos, W. Malaga, L. Guenin-Mace, A. Pawlik, V. Mayau, H. Yahia-Cherbal, W. Frigui, J. Bertrand-Michel, C. Guilhot, C. Demangel

This study shows that Mycobacterium tuberculosis uses host-derived arachidonic acid, a polyunsaturated fatty acid, for growth and immune evasion.

bioRxiv · Jul 8, 2021Immunology

RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection

L. S. Ates, F. Sayes, W. Frigui, R. Ummels, M. P. M. Damen, D. Bottai, M. A. Behr, W. Bitter, L. Majlessi, R. Brosch

This study shows that BCG vaccine strains lack PE_PGRS/PPE-MPTR export due to RD5 inactivation, reducing antigenic repertoire but not vaccine efficacy.

bioRxiv · Feb 14, 2018Microbiology