J. L. Porter

Mycobacterium ulcerans challenge strain selection for a Buruli ulcer controlled human infection model

This paper identifies M. ulcerans JKD8049 as a suitable human challenge strain for Buruli ulcer research due to its stability, antibiotic susceptibility, and ability to produce mycolactone.

A marine sponge-associated mycobacterium closely related to Mycobacterium tuberculosis

This paper describes the discovery of a marine sponge-associated mycobacterium closely related to M. tuberculosis, which shares virulence factors but lacks virulence in mice.

A transmission chain linking Mycobacterium ulcerans with Aedes notoscriptus mosquitoes, possums and human Buruli ulcer cases in southeastern Australia

The paper investigates the transmission chain of Mycobacterium ulcerans between mosquitoes, possums, and humans in southeastern Australia, finding a significant association between M. ulcerans and Aedes notoscriptus mosquitoes.

Structured surveys of Australian native possum excreta predict Buruli ulcer occurrence in humans

This study uses structured surveys of possum excreta to predict human Buruli ulcer cases, showing improved predictive performance compared to null models.

High antibody titres induced by protein subunit vaccines against Buruli ulcer using Mycobacterium ulcerans antigens Hsp18 and MUL_3720

This study evaluates the vaccine potential of M. ulcerans antigens Hsp18 and MUL_3720 in mice, finding high antibody titres but no significant protection against Buruli ulcer.

Vaccine-specific immune responses against Mycobacterium ulcerans infection in a low-dose murine challenge model

This study evaluates a prime-boost vaccine against Mycobacterium ulcerans in mice, finding that both the experimental ER vaccine and BCG provide significant protection through distinct immune profiles.