Author

W. Harper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

J. A. Paulo· 2 shared J. C. Paoli· 2 shared A. Bieber· 1 shared A. Ordureau· 1 shared A. R. Prescott· 1 shared B. A. Schulman· 1 shared C. Capitanio· 1 shared E. Barini· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

J. A. Paulo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Combinatorial selective ER-phagy remodels the ER during neurogenesis

M. J. Hoyer, C. Capitanio, I. R. Smith, J. C. Paoli, A. Bieber, Y. Jiang, J. A. Paulo, M. A. Gonzalez-Lozano, W. Baumeister, F. Wilfling, B. A. Schulman, W. Harper

The paper quantifies ER proteome remodeling during neurogenesis using ER-phagy receptors and identifies receptor-specific ER protein clearance mechanisms.

bioRxiv · Jun 26, 2023Cell Biology

Early Endosome Capture Proteomics and its Application to Amyloid Precursor Protein Intramembrane Processing by β and γ-Secretases

H. Park, Q. Yu, F. V. Hundley, K. Overmyer, L. Serrano, J. A. Paulo, J. C. Paoli, S. Swarup, J. Coon, S. Gygi, W. Harper

This paper develops a method to isolate early endosomes and uses it to study amyloid precursor protein processing by β and γ-secretases in these compartments.

bioRxiv · Mar 31, 2022Cell Biology

Global ubiquitylation analysis of mitochondria in primary neurons identifies physiological Parkin targets following activation of PINK1

O. Antico, A. Ordureau, M. Stevens, F. Singh, M. Gierlinski, E. Barini, M. Rickwood, A. R. Prescott, R. Toth, I. Ganley, W. Harper, M. Muqit

The paper identifies 49 PINK1-dependent ubiquitylated proteins in mouse neurons and develops a resource to visualize mitochondrial ubiquitin sites.

bioRxiv · Apr 1, 2021Biochemistry