Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST
F. Kraus, Y. He, S. Swarup, K. A. Overmyer, J. Brenner, C. Capitanio, A. Bieber, A. Jen, N. M. Nightingale, B. J. Anderson, C. Lee, J. A. Paulo, I. R. Smith, J. M. Plitzko, S. P. Gygi, , J. W. Harper
This study uses nMOST to profile proteo-lipidomics in lysosomal storage disease mutants, revealing autophagy defects and mitochondrial dysfunction.
bioRxiv · Mar 26, 2024Cell Biology