Cell BiologybioRxiv
Disordered C-terminal domain drives spatiotemporal confinement of RNAPII to enhance search for chromatin targets
Y. H. Ling, Z. Ye, C. Liang…·C. Wu
The paper shows that the disordered C-terminal domain of RNAPII confines its diffusion to a subnuclear region, enhancing target search efficiency in yeast.
DOI 10.1038/s41556-024-01382-2