Epigenetic state determines inflammatory sensing in neuroblastoma
A. J. Wolpaw, L. D. Grossmann, M. M. Dong, J. L. Dessau, P. A. Brafford, D. Volgina, A. Rodriguez-Garcia, Y. Uzun, D. J. Powell, K. Tan, M. D. Hogarty, J. M. Maris, C. V. Dang
The paper shows that epigenetic states in neuroblastoma cells determine their response to inflammatory stimuli, with mesenchymal states being more responsive than adrenergic states.
bioRxiv · Jan 27, 2021Cancer Biology