Y.-C. Cheng

Formulation development and comparability studies with an aluminum-salt adjuvanted SARS-CoV-2 Spike ferritin nanoparticle vaccine antigen produced from two different cell lines

This study develops and compares an aluminum-salt adjuvanted SARS-CoV-2 Spike ferritin nanoparticle vaccine antigen produced in two cell lines, showing similar immunogenicity despite differences in glycoforms.

Mechanical transmission of Dengue Virus by Aedes aegypti may influence disease transmission dynamics during outbreaks

This study shows that Aedes aegypti mosquitoes can mechanically transmit Dengue Virus to mice immediately after biting infected mice, impacting outbreak dynamics and suggesting implications for vector control.

PRR14 organizes H3K9me3-modifed heterochromatin at the nuclear lamina

This study identifies PRR14 as a protein that organizes H3K9me3-modified heterochromatin at the nuclear lamina through interactions with HP1.

A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates

This paper describes a ferritin-based nanoparticle vaccine, DCFHP-alum, that induces strong, long-lasting neutralizing antibodies against SARS-CoV-2 variants in non-human primates.

Undergraduate student interest in healthcare career in the context of COVID-19 pandemic

This study assesses changes in undergraduate student interest in healthcare careers during the COVID-19 pandemic using a survey of 297 students, finding increased interest despite pandemic challenges.

Diversification of metazoan Kexin-like proprotein convertases: insights from the leech Helobdella

The paper identifies six Kexin-like proprotein convertases in the last common ancestor of protostomes and deuterostomes and characterizes their functional divergence in the leech Helobdella.