Cell BiologybioRxiv
Novel Kras-mutant murine models of non-small cell lung cancer possessing co-occurring oncogenic mutations and increased tumor mutational burden
R. Salehi-Rad, R. Li, L. M. Tran…·S. M. Dubinett
This paper develops novel Kras-mutant murine NSCLC models with increased TMB and co-occurring mutations, showing enhanced anti-PD-1 efficacy but immunosuppressed TMEs in some models.
DOI 10.1007/s00262-020-02837-9