Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling
L. Sui, Y. Zhao, W. Wang, H. Chi, T. Tian, P. Wu, J. Zhang, Y. Zhao, Z.-K. Wei, Z. Hou, G. Zhou, G. Wang, Z. Wang, Q. Liu
This study identifies how flavivirus prM proteins interact with MDA5 and MAVS to inhibit RLR antiviral signaling, revealing species-dependent immune evasion mechanisms.
bioRxiv · Apr 25, 2022 · PreprintMicrobiology